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COVID-19 And Diabetes

  • October 30, 2021
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  • Christine Nderitu
COVID-19 Diabetes
COVID-19 Diabetes

Concern is growing all over the world due to the increasing number of people who have been infected with COVID-19 then developed diabetes. A global analysis published November 2020 in the journal Diabetes, Obesity and Metabolism, found that up to 14.4% of people who were hospitalized with severe COVID-19 also developed diabetes. This has also been witnessed in India where patients with no history of diabetes have reported elevated blood sugars that has had to be managed with medication, months after recovery. So then, is COVID causing diabetes?

So far there is no evidence that specific elements of the virus are causing diabetes. The prevalence of diabetes is not due to one event, rather due to a combination of disease vulnerabilities, associated with chronic illness and COVID-19-specific mechanisms affecting metabolism.

Diabetes, What Do We Know?

Diabetes is a chronic condition where the blood glucose is too high. This can be either because your pancreas, which produces insulin (the hormone that regulates glucose) does not produce enough insulin or the insulin it produces isn’t effective (type 2 diabetes) or it doesn’t produce any insulin at all (type 1 diabetes).

Second, one can be at risk of diabetes but not develop the disease for years. This is especially true for type 2 diabetes where people at risk generally have an impaired relationship between insulin production and insulin resistance right from birth.

This system can however work for as long as 70 years, maintaining glucose levels within the normal range until primary stressors like diet, physical activity and weight upset that delicate balance and push one to diabetes. There are also acute stressors such as pregnancy, steroids or inflammation from aggressive immune responses like is being seen with COVID, that can bring out high blood sugar in people not known to have diabetes or prediabetes.

Type 1 Diabetes & COVID-19

Research has shown that when one has an infection, the body responds by producing antibodies to fight the infection. However, an aggressive immunity response like is happening with COVID can result in increased production of all antibodies including pre-existing ones such as those that attack the islet cells of the pancreas. This then results in high blood sugars as the destruction of cells impairs insulin production.

Type 2 Diabetes & COVID-19

In Kenya for instance, there are many people living with diabetes but do not know it. In such a cases, COVID only enables it to be diagnosed. Doctors from around the world have also argued that a person could be prediabetic, or have a genetical risk with mild stressors such as being overweight and mildly sedentary, and the inflammation from the virus or the high steroids that are being used to help reduce inflammation in the lungs and minimize damage from the immunity response, could push them in to diabetes.

Now steroids increase blood sugar levels through various mechanisms; they block insulin action and increase insulin resistance, reduce glucose uptake in the muscles and adipose tissues, increase production for glucose by the liver by enhancing the effect of hormones that counter insulin, or even directly may reduce the action of the beta cells.

What someone with prediabetes needs to keep in mind is that they are more likely to be diagnosed with type 2 diabetes within 5 years, or at least in their lifetime. Even so, you can delay the progression.

How Can You Prevent Diabetes After COVID-19?

Weight is major risk factor for diabetes, and you are more likely to succeed with it when you do not smoke, engage in physical activity and have better nutrition. Further, data from people with prediabetes shows that losing 6.8 kg to start, can help to slow the progression to type 2 diabetes.

Remember to take a diabetes test at your first post-discharge visit, at six months post-discharge and then annually.

References and Additional Reading about Covid- 19 & Diabetes

  1. COVID-19 and diabetes: VCU health experts answers your questions – Here
  2. CDC People with Certain Medical Conditions – Here
  3. The Lancet COVID-19 and diabetes – Here

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